On November 16, 2024, the XI Narcolepsy Seminar brought together leading international experts, researchers, and clinicians in Bologna at the Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna. This multidisciplinary meeting has become pivotal for discussing advancements in diagnosing, treating, and managing narcolepsy.
Fostering Collaboration: The Italian Narcolepsy Network
A central theme of this year’s seminar was the development of the Italian Narcolepsy Network, aiming to enhance national collaboration in clinical management and research. Discussions focused on the state of the ReN&IS Icilio Ceretelli national registry and the critical role of biobanks, such as the IRCCS ISNB biobank, in improving the understanding of narcolepsy and related conditions.
Highlights from the Scientific Program
The seminar featured a rich program of presentations and discussions. Under the moderation of Prof. Raffaele Ferri, Prof. Emmanuel Mignot opened with an insightful “Year in Review,” highlighting key research breakthroughs in narcolepsy. Prof. Alessandro Silvani followed with a session on translational research, emphasizing the bridge between basic science and clinical applications.
Wearable technology’s emerging role in diagnosing narcolepsy borderland cases was discussed by Dr. Oriella Gnarra, shedding light on how digital health tools can refine diagnostic accuracy and improve patient monitoring.
Another critical session, led by Prof. Fabio Pizza, scientific coordinator of the event, explored telemedicine’s role in narcolepsy care, particularly through initiatives like the TENAR trial, which evaluates digital tools for early detection and intervention.
Beyond medical interventions, Prof. Christian Franceschini presented psychological approaches to improving patient well-being, underlining the importance of multidisciplinary care.
The session on biobanks featured contributions from Dr. Rolf Fronczek and Prof. Raffaele Lodi and Dr. Francesco Colaci demonstrate how cutting-edge genetic and biomarker research is advancing personalized medicine for narcolepsy.
The meeting concluded with a discussion on the future of narcolepsy care in Italy, led by the president, Prof. Giuseppe Plazzi, emphasizing the importance of structured national collaboration and research synergy.
Workshops and Clinical Case Discussions
In the afternoon, participants engaged in interactive workshops covering key clinical challenges, including:
Certification processes for narcolepsy and idiopathic hypersomnia
Complex diagnostic cases within the narcolepsy spectrum
Treatment strategies for idiopathic hypersomnia, guided by real-world cases
These hands-on sessions provided a platform for in-depth discussions on best practices and evolving therapeutic strategies.
A Dedicated Session for Patients and Associations
In addition to the scientific sessions, the event included a special session reserved for patients with narcolepsy, organized in collaboration with patient associations. This parallel session provided a unique opportunity for patients and their families to connect with healthcare professionals, exchange experiences, and gain insights into ongoing research, therapeutic options, and patient rights. The participation of patient associations further emphasized the importance of a patient-centered approach in the management of narcolepsy and the need for stronger interaction between clinicians, researchers, and those directly affected by the disorder.
Looking Ahead: Strengthening Multidisciplinary Care
The XI Narcolepsy Seminar reinforced the need for multidisciplinary approaches in managing narcolepsy, integrating neurology, psychology, digital health, and genetic research. The establishment of the Italian Narcolepsy Network represents a promising step toward better patient care and scientific advancement.
With strong participation from international experts, clinicians, and patient representatives, this event marked another milestone in the collaborative effort to improve diagnosis, treatment, and support for people living with narcolepsy.
